2-F-2-ara-N2-ibu-dG Phosphoramidite [1404463-20-2]

MedChem Express

2-F-2-ara-N2-ibu-dG Phosphoramidite [1404463-20-2]

5

1404463-20-2

Research Use Only

C45H54FN6O8P

856.92

2-F-2-ara-N2-ibu-dG Phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

O=C1NC(NC(C(C)C)=O)=NC2=C1N=CN2[C@@H]3O[C@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)[C@@H](OP(OCCC#N)C(C(C)C)C(C)C)[C@@H]3F

12352005