2-Hexyl-4-pentynoic acid

MedChem Express

2-Hexyl-4-pentynoic acid [96017-59-3]

5

96017-59-3

Research Use Only

98.0

C11H18O2

182.26

2-Hexyl-4-pentynoic acid ((+/-)-2-Hexyl-4-pentynoic acid), valproic acid (VPA) derivative, exhibits potential roles of HDAC inhibition ( IC 50 =13 microM) and HSP70 induction. Potent neuroprotective effects. 2-Hexyl-4-pentynoic acid causes histone hyperacetylation and protect against glutamate-induced excitotoxicity in cultured neurons [1] . 2-Hexyl-4-pentynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

CCCCCCC(CC#C)C(O)=O

-20°C

12352200