2-O-(2-Azidoethyl)adenosine [2226475-42-7]
HY-152870
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product Name2-O-(2-Azidoethyl)adenosine [2226475-42-7]
- Delivery Days Customer10
- CAS Number2226475-42-7
- CertificationResearch Use Only
- Molecular FormulaC12H16N8O4
- Molecular Weight336.31
- Scientific Description2-O-(2-Azidoethyl)adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 2-O-(2-Azidoethyl)adenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- SMILESOC[C@@H]1[C@@H](O)[C@@H](OCCN=[N+]=[N-])[C@H](N2C=NC3=C2N=CN=C3N)O1
- UNSPSC41115811