2-O-2-Propyn-1-ylguanosine [206552-86-5]

MedChem Express

2-O-2-Propyn-1-ylguanosine [206552-86-5]

10

206552-86-5

Research Use Only

C13H15N5O5

321.29

2-O-2-Propyn-1-ylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1]. 2-O-2-Propyn-1-ylguanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

O[C@H]1[C@@H](OCC#C)[C@H](N(C=N2)C3=C2C(NC(N)=N3)=O)O[C@@H]1CO

41115811