2-O-2-Propyn-1-ylguanosine [206552-86-5]
HY-152684
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product Name2-O-2-Propyn-1-ylguanosine [206552-86-5]
- Delivery Days Customer10
- CAS Number206552-86-5
- CertificationResearch Use Only
- Molecular FormulaC13H15N5O5
- Molecular Weight321.29
- Scientific Description2-O-2-Propyn-1-ylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1]. 2-O-2-Propyn-1-ylguanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- SMILESO[C@H]1[C@@H](OCC#C)[C@H](N(C=N2)C3=C2C(NC(N)=N3)=O)O[C@@H]1CO
- UNSPSC41115811