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2-O-Methyluridine [2140-76-3]

HY-W011824
MedChem Express
CAS Number2140-76-3
Product group Chemicals
Estimated Purity99.81
Molecular Weight258.23
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Overview

  • Supplier
    MedChem Express
  • Product Name
    2-O-Methyluridine [2140-76-3]
  • Delivery Days Customer
    5
  • CAS Number
    2140-76-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.81
  • Molecular Formula
    C10H14N2O6
  • Molecular Weight
    258.23
  • Scientific Description
    2-O-Methyluridine is a modified nucleoside that can be found in T. thermophile tRNA. 2-O-Methyluridine can be incorporated into siRNA targeting the gene encoding apolipoprotein B, which decreases ApoB protein levels in HepG2 and prevents IFN-alpha production in isolated human PBMCs. 2-O-Methyluridine level in serum is decreased in patients with breast cancer[1][2][3].
  • SMILES
    O[C@H]1[C@@H](OC)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1CO
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200