2-Thiouridine [20235-78-3]
HY-117813
CAS Number20235-78-3
Product group Chemicals
Estimated Purity99.76
Molecular Weight260.27
Overview
- SupplierMedChem Express
- Product Name2-Thiouridine [20235-78-3]
- Delivery Days Customer5
- CAS Number20235-78-3
- CertificationResearch Use Only
- Estimated Purity99.76
- Molecular FormulaC9H12N2O5S
- Molecular Weight260.27
- Scientific Description2-Thiouridine is an orally active modified nucleobase. 2-Thiouridine stabilizes U:A base pairs and destabilizes U:G wobble base pairs. 2-Thiouridine significantly improves the efficiency and accuracy of nonenzymatic replication of mixed-sequence A/U-containing RNA templates. 2-Thiouridine exhibits antiviral activity against multiple positive-sense single-stranded RNA viruses (DENV2, ZIKV, YFV, JEV, WNV, CHIKV, human coronaviruses ( [HCoV]-229E, HCoV-OC43, SARS-CoV), and MERS-CoV)[1][2][3][4].
- SMILESS=C(N1)N([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)C=CC1=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
![2-Thiouridine [20235-78-3]](https://www.targetmol.com/group3/M00/37/DB/CgoaEGayUsCEJT_gAAAAAMgFqU4482.png)