20-HEPE [116477-57-7]
HY-121888
CAS Number116477-57-7
Product group Chemicals
Molecular Weight318.45
Overview
- SupplierMedChem Express
- Product Name20-HEPE [116477-57-7]
- Delivery Days Customer5
- CAS Number116477-57-7
- CertificationResearch Use Only
- Molecular FormulaC20H30O3
- Molecular Weight318.45
- Scientific Description20-HEPE is a metabolite of eicosapentaenoic acid formed by omega-oxidation of EPA by cytochrome P450 (CYP) omega-oxidases, including human CYP4F3B. At 10 microM, it activates peroxisome proliferator-activated receptor alpha (PPARalpha) in COS-7 cells expressing a luciferase reporter gene. 20-HEPE also activates mouse transient receptor potential vanilloid receptor 1 (mTRPV1) in vitro but lacks analgesic activity in rats.
- SMILESOCC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O
- UNSPSC12352200