20(S)-Hydroxycholesterol

MedChem Express

20(S)-Hydroxycholesterol [516-72-3]

10

516-72-3

Research Use Only

99.29

C27H46O2

402.65

20(S)-hydroxyCholesterol (20alpha-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC 50 of 3 microM in a gene transcription reporter assay using NIH3T3 cells [1] [2] .

C[C@@]1([C@@]2([H])[C@@](C)(O)CCCC(C)C)[C@](CC2)([H])[C@@](CC=C3[C@@]4(CC[C@H](O)C3)C)([H])[C@]4([H])CC1

-20°C,2°C to 8°C

12352200