20S Proteasome-IN-2

MedChem Express

20S Proteasome-IN-2 [2028300-31-2]

10

Research Use Only

C30H44N4O8S

620.76

20S Proteasome-IN-2 is a human 20S proteasome inhibitor. 20S Proteasome-IN-2 shows high selectivity to its beta5 subunit with the IC50 of 0.18 microM. 20S Proteasome-IN-2 displays anti-proliferative effect in vitro and in vivo, and arrests cell cycle at G2/M[1].

O=C(N[C@@H](COC)C(N[C@@H](CC(C)C)C(C1=CC=CO1)=O)=O)[C@@H](NS(=O)(C2=CC=C(C)C=C2)=O)CC(NCC(C)(C)C)=O

12131703