20S Proteasome-IN-4 [2827061-47-0]

MedChem Express

20S Proteasome-IN-4 [2827061-47-0]

10

2827061-47-0

Research Use Only

C20H18ClF2N3O3

421.83

20S Proteasome-IN-4 (Compound 7) is a brain-penetrant, parasite-selective, orally active 20S proteasome inhibitor with an IC50 of 6.3 nM against T. b. brucei 20S proteasome. 20S Proteasome-IN-4 can be used for the research of human African trypanosomiasis (HAT)[1].

ClC1=CC=C2C(C(NC3=CC=CC(F)=C3F)=CC(C(NC[C@H](CO)OC)=O)=N2)=C1

12131703