2,3-Dideoxy-5-ethyluridine [108895-49-4]
HY-116240
CAS Number108895-49-4
Product group Chemicals
Molecular Weight240.26
Overview
- SupplierMedChem Express
- Product Name2,3-Dideoxy-5-ethyluridine [108895-49-4]
- Delivery Days Customer9
- CAS Number108895-49-4
- CertificationResearch Use Only
- Molecular FormulaC11H16N2O4
- Molecular Weight240.26
- Scientific Description2,3-Dideoxy-5-ethyluridine (ddEtUrd) is an antiretroviral compound with weak anti-HIV activity. The 3-substituted derivatives of 2,3-Dideoxy-5-ethyluridine did not show significant antiviral effects. 2,3-Dideoxy-5-ethyluridine was less potent in inhibiting HIV replication in human MT4 lymphocytes. Although phosphorylation induced by 2,3-Dideoxy-5-ethyluridine is essential for antiviral activity, there is no strong correlation between its affinity for human dThd kinase or dCyd kinase[1].
- SMILESOC[C@@H]1CC[C@H](N2C=C(CC)C(NC2=O)=O)O1
- UNSPSC12352200