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2,5-Di-tert-butylhydroquinone [88-58-4]

HY-W012399
MedChem Express
CAS Number88-58-4
Product group Chemicals
Estimated Purity99.90
Molecular Weight222.33
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Overview

  • Supplier
    MedChem Express
  • Product Name
    2,5-Di-tert-butylhydroquinone [88-58-4]
  • Delivery Days Customer
    9
  • CAS Number
    88-58-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.90
  • Molecular Formula
    C14H22O2
  • Molecular Weight
    222.33
  • Scientific Description
    2,5-Di-tert-butylhydroquinone (BHQ) (Compound 2), an indirect food additive, is a Sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) inhibitor with an IC50 of 400 nM. 2,5-Di-tert-butylhydroquinone disrupts the gating function of the residue Glu309 which prevents Ca2+ from reaching their binding site. 2,5-Di-tert-butylhydroquinone regulates the activity of 5-lipoxygenase and COX-2 (IC50: 1.8 and 14.1 microM for 5-LO and COX-2, respectively)[1][2].
  • SMILES
    OC1=CC(C(C)(C)C)=C(O)C=C1C(C)(C)C
  • Storage Instruction
    RT
  • UNSPSC
    12352200