25-Hydroxycholesterol [2140-46-7]

TargetMol Chemicals

25-Hydroxycholesterol [2140-46-7]

9

2140-46-7

Research Use Only

25-Hydroxycholesterol

98.73%

C27H46O2

402.65

25-Hydroxycholesterol is a steroid derivative that suppresses the cleavage of sterol regulatory element binding proteins (SREBPs). It inhibits HMG-CoA reductase and so it also plays a significant role in the in vivo regulation of cholesterol biosynthesis after an acute dietary cholesterol challenge. 25-hydroxycholesterol is a potent (EC50~65 nM) and selective suppressor of IgA production by B cells.

3 years

C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

-20°C

12352200