3-Acetyl-7-Hydroxycoumarin [10441-27-7]

MedChem Express

3-Acetyl-7-Hydroxycoumarin [10441-27-7]

5

10441-27-7

Research Use Only

C11H8O4

204.18

3-Acetyl-7-Hydroxycoumarin (Compound 2) is a high selective 17-beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) inhibitor. 3-Acetyl-7-Hydroxycoumarin shows a significant improvement of the inhibitory potency, with 57% inhibition of 17beta-HSD1 at 6 microM. 3-Acetyl-7-Hydroxycoumarin is promising for research of hormone-dependent diseases, such as breast cancer and endometriosis[1].

CC(=O)C1=CC2=C(C=C(C=C2)O)OC1=O

12352200