3-Acetyl-7-Hydroxycoumarin

MedChem Express

3-Acetyl-7-Hydroxycoumarin [10441-27-7]

5

Research Use Only

3-Acetyl-7-Hydroxycoumarin (Compound 2) is a high selective 17-beta-hydroxysteroid dehydrogenase type 1 ( 17beta-HSD1 ) inhibitor. 3-Acetyl-7-Hydroxycoumarin shows a significant improvement of the inhibitory potency, with 57% inhibition of 17beta-HSD1 at 6 microM. 3-Acetyl-7-Hydroxycoumarin is promising for research of hormone-dependent diseases, such as breast cancer and endometriosis [1] .

12352200