Bio-Connect

3-Azido-3-deoxy-2-thiouridine [2305416-00-4]

HY-152353
MedChem Express
Product group Molecular Biology
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    MedChem Express
  • Product Name
    3-Azido-3-deoxy-2-thiouridine [2305416-00-4]
  • Delivery Days Customer
    10
  • CAS Number
    2305416-00-4
  • Certification
    Research Use Only
  • Molecular Formula
    C9H11N5O4S
  • Molecular Weight
    285.28
  • Scientific Description
    3-Azido-3-deoxy-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 3-Azido-3-deoxy-2-thiouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
  • SMILES
    O=C(N1)C=CN([C@@H]2O[C@H](CO)[C@@H](N=[N+]=[N-])[C@H]2O)C1=S
  • UNSPSC
    41115811