3-Azido-3-deoxy-5-methylcytidine [1282040-14-5]

MedChem Express

3-Azido-3-deoxy-5-methylcytidine [1282040-14-5]

10

1282040-14-5

Research Use Only

99.90

C10H14N6O4

282.26

3-Azido-3-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 microM in MCF-7 cells. 3-Azido-3-deoxy-5-methylcytidine also inhibits HIV-1 reverse transcriptase with an EC50 of 0.06 microM in peripheral blood mononuclear (PBM) cells[1]. 3-Azido-3-deoxy-5-methylcytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O[C@@H]1[C@H](N=[N+]=[N-])[C@@H](CO)O[C@H]1N2C=C(C)C(N)=NC2=O

-20°C,2°C to 8°C

12352200