3-Azido-3-deoxy-5-methyluridine [215176-58-2]
HY-152645
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product Name3-Azido-3-deoxy-5-methyluridine [215176-58-2]
- Delivery Days Customer10
- CAS Number215176-58-2
- CertificationResearch Use Only
- Molecular FormulaC10H13N5O5
- Molecular Weight283.24
- Scientific Description3-Azido-3-deoxy-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 3-Azido-3-deoxy-5-methyluridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- SMILESOC[C@@H]1[C@@H](N=[N+]=[N-])[C@@H](O)[C@H](N(C=C2C)C(NC2=O)=O)O1
- UNSPSC41115811