3-Azido-3-deoxy-beta-L-adenosine [216976-76-0]
HY-152601
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product Name3-Azido-3-deoxy-beta-L-adenosine [216976-76-0]
- Delivery Days Customer10
- CAS Number216976-76-0
- CertificationResearch Use Only
- Molecular FormulaC10H12N8O3
- Molecular Weight292.25
- Scientific Description3-Azido-3-deoxy-beta-L-adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 3-Azido-3-deoxy-beta-L-adenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- SMILESO[C@H]1[C@@H](N=[N+]=[N-])[C@H](CO)O[C@@H]1N2C3=C(C(N)=NC=N3)N=C2
- UNSPSC41115811