3-Azido-3-deoxyuridine [70580-88-0]

MedChem Express

3-Azido-3-deoxyuridine [70580-88-0]

5

70580-88-0

Research Use Only

99.97

C9H11N5O5

269.21

3-Azido-3-deoxyuridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 3-Azido-3-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

OC[C@@H]1[C@@H](N=[N+]=[N-])[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O1

-20°C

41106300