3-Azido-N6-benzoyl-3-deoxyadenosine [103597-10-0]
HY-154579
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product Name3-Azido-N6-benzoyl-3-deoxyadenosine [103597-10-0]
- Delivery Days Customer10
- CAS Number103597-10-0
- CertificationResearch Use Only
- Molecular FormulaC17H16N8O4
- Molecular Weight396.36
- Scientific Description3-Azido-N6-benzoyl-3-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 3-Azido-N6-benzoyl-3-deoxyadenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- SMILESOC[C@@H]1[C@@H](N=[N+]=[N-])[C@@H](O)[C@H](N2C(N=CN=C3NC(C4=CC=CC=C4)=O)=C3N=C2)O1
- UNSPSC41115811