3-beta-C-Ethynylguanosine [180300-56-5]

MedChem Express

3-beta-C-Ethynylguanosine [180300-56-5]

10

180300-56-5

Research Use Only

C12H13N5O5

307.26

3-beta-C-Ethynylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1]. 3-beta-C-Ethynylguanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

OC[C@@H]1[C@](O)(C#C)[C@@H](O)[C@H](N2C=NC3=C2N=C(N)NC3=O)O1

41115811