3-Chlorodiphenylamine

MedChem Express

3-Chlorodiphenylamine [101-17-7]

5

101-17-7

Research Use Only

98.74

C12H10ClN

203.67

3-Chlorodiphenylamine is a high affinity Ca2+ sensitizer of cardiac muscle. 3-Chlorodiphenylamine is based on diphenylamine and binds to the isolated N-domain of cardiac troponin C (cTnC) (Kd=6 microM). 3-Chlorodiphenylamine is an excellent starting scaffold for the development of more potent Ca2+-sensitizing compounds due to its small size, and can be used for systolic heart failure research[1].

ClC1=CC(NC2=CC=CC=C2)=CC=C1

-20°C,2°C to 8°C

12352200