3-Deoxyglucosone [4084-27-9]

TargetMol Chemicals

3-Deoxyglucosone [4084-27-9]

9

4084-27-9

Chemical

Research Use Only

3-Deoxyglucosone

C6H10O5

162.14

3-Deoxyglucosone(3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with protein amino groups to form advanced glycosylated end proteins (AGEs).3-Deoxyglucosone inactivates glutathione peroxidase and synergizes with low glucose to enhance GLP-1 secretion.3-Deoxyglucosone is used as a biomarker for diabetes mellitus.3-Deoxyglucosone has been shown to be an inhibitor of GLP-1 secretion in the presence of low glucose. 3-Deoxyglucosone inactivates glutathione oxidase, synergizes with low glucose to enhance GLP-1 secretion, and can be used as a biologic marker for diabetes.

3 years

[C@H](CC(C=O)=O)([C@@H](CO)O)O

-20°C

12352200