3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles [287196-91-2]

TargetMol Chemicals

3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles [287196-91-2]

9

Research Use Only

C11H6F3N3OS

285.25

3-Hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles serves as an inhibitor of both bone morphogenetic protein 2 (BMP2), with an IC50 value of 2.2 microM, and mitogen-activated protein kinase 1 (MEK1). Additionally, this compound demonstrates anti-inflammatory and neuroprotective effects in an EAE mouse model.

N#CC=1C(=O)NSC1NC=2C=CC=CC2C(F)(F)F

-20°C

12352200