3-Methyl-L-tyrosine [17028-03-4]

MedChem Express

3-Methyl-L-tyrosine [17028-03-4]

5

17028-03-4

Research Use Only

C10H13NO3

195.22

3-Methyl-L-tyrosine is a derivative of L-Tyrosine (HY-N0473). Structurally, 3-Methyl-L-tyrosine features a methyl modification at the third position of the aromatic ring of L-Tyrosine. As a substrate for the protein tyrosine kinase Csk, 3-Methyl-L-tyrosines relative catalytic efficiency (kcat/Km) is 38% of L-Tyrosine, indicating that the methyl modification impacts the processing efficiency of Gsk significantly. 3-Methyl-L-tyrosine helps to deepen the understanding of Gsks molecular recognition mechanisms of its substrates, which is crucial for developing specific inhibitors targeting Gsk[1].

CC1=CC(=CC=C1O)C[C@@H](C(=O)O)N

12352200