3-O-Me-G(iBu)-2-phosphoramidite [179479-04-0]

MedChem Express

3-O-Me-G(iBu)-2-phosphoramidite [179479-04-0]

5

179479-04-0

Research Use Only

C44H54N7O9P

869.94

3-O-Me-G(iBu)-2-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

O=C1C2=C(N([C@H]3[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@H](OC)[C@@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)O3)C=N2)NC(NC(C(C)C)=O)=N1

12352005