3-O-MOE-G(iBu)-2-phosphoramidite [256224-06-3]

MedChem Express

3-O-MOE-G(iBu)-2-phosphoramidite [256224-06-3]

10

256224-06-3

Research Use Only

C47H60N7O10P

913.99

3-O-MOE-G(iBu)-2-phosphoramidite is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].

COCCO[C@H]1[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@H](N2C(N=C(NC(C(C)C)=O)NC3=O)=C3N=C2)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6

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