3M-011

Biorbyt

3M-011

10

642473-62-9

Research Use Only

C18H25N5O3S

391.49

3M-011 is a potent TLR7/8 agonist and cytokine inducer; stimulates type I interferon (IFN) and other cytokines such as TNF-alpha, IL-12, and IFN-gamma from rat peripheral blood mononuclear cells; induces IL-12 and COX-2 expression in mDC from HIV+ and HIV- individuals, and inhibits H3N2 influenza viral replication in the nasal cavity; potentiates NK cytotoxicity, and shows antitumor effects in scid/B6 mice and scid/NOD mice.

CS(=O)(NC(C)(C)CN1C(COCC)=NC2=C1C3=CC=CC=C3N=C2N)=O

12352200