4-(Aminomethyl)fluorescein hydrochloride [91539-64-9]

Chemodex

4-(Aminomethyl)fluorescein hydrochloride [91539-64-9]

2

91539-64-9

Research Use Only

>97%

C21H16ClNO5

397.81

4-(Aminomethyl)fluorescein is an excellent building block for developing fluoresceinated bioconjugates. Its amino group readily reacts with activated carboxy esters (such as NHS ester). The primary aliphatic amine of 4-(aminomethyl)fluorescein can be reversibly coupled to aldehydes and ketones to form a Schiff base, which can be reduced to a stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNBH3) to form new probes. Carboxylic acids of proteins and other water-soluble biopolymers can be coupled to this molecule in aqueous solution using water-soluble carbodiimides such as EDAC. Spectral Data: lambdaex 494 nm; lambdaem 520 nm. - Chemical. CAS: 91539-64-9. Formula: C21H16ClNO5. MW: 397.81. 4-(Aminomethyl)fluorescein is an excellent building block for developing fluoresceinated bioconjugates. Its amino group readily reacts with activated carboxy esters (such as NHS ester). The primary aliphatic amine of 4-(aminomethyl)fluorescein can be reversibly coupled to aldehydes and ketones to form a Schiff base, which can be reduced to a stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNBH3) to form new probes. Carboxylic acids of proteins and other water-soluble biopolymers can be coupled to this molecule in aqueous solution using water-soluble carbodiimides such as EDAC. Spectral Data: lambdaex 494 nm; lambdaem 520 nm.

OC1=CC=C(C(C2=CC=CC=C2C(O)=O)=C(C=C3)C(O4)=C(CN)C3=O)C4=C1.Cl

-20°C

12162000