4-Epidoxycycline [6543-77-7]

MedChem Express

4-Epidoxycycline [6543-77-7]

5

6543-77-7

Research Use Only

C22H24N2O8

444.43

4-Epidoxycycline is a liver metabolite of the antibiotic doxycycline (doxycycline, HY-N0565) and doesnt have antibiotic properties in mice. 4-Epidoxycyclines ability to regulate HER2 gene expression in vitro and in live mouse models is similar to that of doxycycline, and it shows comparable high efficacy in tumor tissues, achieving over 95% tumor regression rates[1].

O=C(C(C1=O)=C(O)[C@H](N(C)C)[C@]2([H])[C@@H](O)[C@]3([H])[C@@H](C)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4)N

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