4-fluorouridine (4-FlU, EIDD-2749)

Biorbyt

4-fluorouridine (4-FlU, EIDD-2749)

10

Research Use Only

C9H11FN2O6

262.19

4-fluorouridine (4-FlU, EIDD-2749) is a ribonucleoside analog that inhibits respiratory syncytial virus (RSV), related RNA viruses, and SARS-CoV-2 with high selectivity index (EC50/CC50 of ≥1877) in cells and human airway epithelia organoids. 4-FlU induces a delayed stalling of RSV and SARS-CoV-2 RdRP (RNA-dependent RNA polymerase).

O=C1NC(N([C@@H]2O[C@@](CO)(F)[C@@H](O)[C@H]2O)C=C1)=O

12352200