4-Hydroperoxy cyclophosphamide

MedChem Express

4-Hydroperoxy cyclophosphamide [39800-16-3]

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4-Hydroperoxy cyclophosphamide is the active metabolite form of the precursor Cyclophosphamide. 4-Hydroperoxy cyclophosphamide cross-links DNA to induce T cell apoptosis independent of caspase receptor activation, and can activate the mitochondrial death pathway by producing reactive oxygen species ( ROS ). 4-Hydroperoxy cyclophosphamide can be used in the study of rheumatoid arthritis and autoimmune diseases [1] [2] .

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