4-Hydroperoxy Cyclophosphamide-d4 [1246816-71-6]

MedChem Express

4-Hydroperoxy Cyclophosphamide-d4 [1246816-71-6]

10

1246816-71-6

Research Use Only

95.0

C7H11D4Cl2N2O4P

297.11

4-Hydroperoxy Cyclophosphamide-d4 is the deuterium labeled 4-Hydroperoxy cyclophosphamide. 4-Hydroperoxy cyclophosphamide is the active metabolite form of the proagent Cyclophosphamide. 4-Hydroperoxy cyclophosphamide crosslinks DNA and induces T cell apoptosis independent of death receptor activation, but activates mitochondrial death pathways through production of reactive oxygen species (ROS). 4-Hydroperoxy cyclophosphamide has the potential for lymphomas and autoimmune disorders[1][2].

N(CC(Cl)([2H])[2H])(CC(Cl)([2H])[2H])P1(=O)NC(OO)CCO1

-80°C

41115800