4-Hydroxychalcone [20426-12-4]

MedChem Express

4-Hydroxychalcone [20426-12-4]

10

20426-12-4

Research Use Only

99.29

C15H12O2

224.25

4-Hydroxychalcone is a chalcone metabolite with anti-angiogenic and anti-inflammatory activities. 4-Hydroxychalcone suppresses angiogenesis by suppression of growth factor pathway with no signs of cytotoxicity[1]. 4-Hydroxychalcone inhibits TNF-alpha induced NF-kappaB pathway activation and activates BMP signaling, reduces resistant hypertension (RH) by attenuating hyperaldosteronism and renal injury in mice[2].

O=C(C1=CC=CC=C1)/C=C/C2=CC=C(O)C=C2

2°C to 8°C

12352200