4-Hydroxychalcone

MedChem Express

4-Hydroxychalcone [2657-25-2]

10

2657-25-2

99.66

C15H12O2

224.25

4-Hydroxychalcone is a chalcone isolated from licorice root, with hepatoprotective activity. 4-Hydroxychalcone inhibits TNFalpha-induced NF-kappaB activation via proteasome inhibition. 4-Hydroxychalcone induces a rapid potassium release from mitochondrial vesicles and causes deterioration of respiratory control and oxidative phosphorylation of isolated rat liver mitochondria [1] [2] [3] .

O=C(C1=CC=C(O)C=C1)/C=C/C2=CC=CC=C2

-20°C,2°C to 8°C

12352200