4-Methylesculetin

MedChem Express

4-Methylesculetin [529-84-0]

10

529-84-0

Research Use Only

98.32

C10H8O4

192.17

4-Methylesculetin is an orally active coumarin derivative, with potent anti-oxidant and anti-inflammatory activities. 4-Methylesculetin inhibits myeloperoxidase activity. 4-Methylesculetin protects bone resorption by reducing the elevated levels of bone-joint exoglycosidases, cathepsin-D and tartrate resistant acid phosphatases. 4-Methylesculetin ameliorats the upregulated non-enzymatic inflammatory markers like TNF-alpha, IL-1beta, IL-6, COX-2 and PGE2, which is promising for research of inflammatory diseases [1] [2] .

O=C1C=C(C)C2=CC(O)=C(O)C=C2O1

2°C to 8°C

12352200