4-MU-alpha-GlcNS (sodium) [460085-45-4]

MedChem Express

4-MU-alpha-GlcNS (sodium) [460085-45-4]

10

460085-45-4

Research Use Only

99.81

C16H18NNaO10S

439.37

4-MU-alpha-GlcNS sodium is a fluorogenic substrate of heparin sulphamidase, is desulfurized into 4-MU-alpha-GlcNH2. 4-MU-alpha-GlcNH2 can liberate 4-methylumbelliferone (4-MU, fluorescent product) via alpha-glucosaminidase catalysis, with the emission wavelength maxima of 445-454 nm. 4-MU-alpha-GlcNS sodium can be used to heparin sulphamidase deficiencies associated with Mucopolisaccaridosis IIIA and other lysosomal disorders researches[1][2][3].

O=S(N[C@H]([C@H]([C@@H]([C@H](O1)CO)O)O)[C@H]1OC2=CC=C(C(C)=CC(O3)=O)C3=C2)(O[Na])=O

2°C to 8°C

12162000