4E-BP1 (phospho Thr37/Thr46) antibody [HL3276]

GeneTex

4E-BP1 (phospho Thr37/Thr46) antibody [HL3276]

7

WB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Monoclonal

HL3276

1 mg/ml

Unconjugated

EIF4EBP1

eukaryotic translation initiation factor 4E binding protein 1

4EBP1; 4E-BP1; BP-1; eIF4E-binding protein 1; eukaryotic translation initiation factor 4E-binding protein 1; PHAS-I; phosphorylated heat- and acid-stable protein regulated by insulin 1

Rabbit

IgG

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5 end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008]

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203