5-(2-Azidoethyl)uridine
HY-154256
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product Name5-(2-Azidoethyl)uridine
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC11H17N5O6
- Molecular Weight315.28
- Scientific Description5-(2-Azidoethyl)uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 5-(2-Azidoethyl)uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- SMILESOC[C@@H]1[C@H](O)[C@H](O)[C@H](N2CC(CCN=[N+]=[N-])C(NC2=O)=O)O1
- UNSPSC41115811