5-(3-Azidopropyl)cytidine

MedChem Express

5-(3-Azidopropyl)cytidine

10

Research Use Only

C12H18N6O5

326.31

5-(3-Azidopropyl)cytidine is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1]. 5-(3-Azidopropyl)cytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O[C@H]1[C@@H](O)[C@H](N2C=C(CCCN=[N+]=[N-])C(N)=NC2=O)O[C@@H]1CO

41115811