5-Azido-5-deoxy-2-O-methyl-5-methyluridine [187733-73-9]
HY-154377
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product Name5-Azido-5-deoxy-2-O-methyl-5-methyluridine [187733-73-9]
- Delivery Days Customer10
- CAS Number187733-73-9
- CertificationResearch Use Only
- Molecular FormulaC11H15N5O5
- Molecular Weight297.27
- Scientific Description5-Azido-5-deoxy-2-O-methyl-5-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 5-Azido-5-deoxy-2-O-methyl-5-methyluridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- SMILESO=C(C(C)=C1)NC(N1[C@@H]2O[C@H](CN=[N+]=[N-])[C@@H](O)[C@H]2OC)=O
- UNSPSC41115811