5-Azido-5-deoxy-2-O-methyluridine [194034-68-9]
HY-154308
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product Name5-Azido-5-deoxy-2-O-methyluridine [194034-68-9]
- Delivery Days Customer10
- CAS Number194034-68-9
- CertificationResearch Use Only
- Molecular FormulaC9H11N5O5
- Molecular Weight269.21
- Scientific Description5-Azido-5-deoxy-2-O-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 5-Azido-5-deoxy-2-O-methyluridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- SMILESO[C@H]1[C@@H](OC)[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]1N=[N+]=[N-]
- UNSPSC41115811