5-Azido-5-deoxyadenosine [737-76-8]
HY-154054
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product Name5-Azido-5-deoxyadenosine [737-76-8]
- Delivery Days Customer10
- CAS Number737-76-8
- CertificationResearch Use Only
- Molecular FormulaC10H12N8O3
- Molecular Weight292.25
- Scientific Description5-Azido-5-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 5-Azido-5-deoxyadenosine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- SMILESO[C@@H]1[C@@H](CN=[N+]=[N-])O[C@@H](N2C(N=CN=C3N)=C3N=C2)[C@@H]1O
- UNSPSC41115811