5-Azido-5-deoxyuridine [39483-48-2]
HY-154405
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product Name5-Azido-5-deoxyuridine [39483-48-2]
- Delivery Days Customer10
- CAS Number39483-48-2
- CertificationResearch Use Only
- Molecular FormulaC9H11N5O5
- Molecular Weight269.21
- Scientific Description5-Azido-5-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 5-Azido-5-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- SMILESO=C(C=C1)NC(N1[C@@H]2O[C@H](CN=[N+]=[N-])[C@@H](O)[C@H]2O)=O
- UNSPSC41115811