5-Azidomethyl-2-beta-methyl-2,3,5-tri-O-benzoyluridine [2305416-08-2]

MedChem Express

5-Azidomethyl-2-beta-methyl-2,3,5-tri-O-benzoyluridine [2305416-08-2]

10

2305416-08-2

Research Use Only

C32H27N5O9

625.58

5-Azidomethyl-2-beta-methyl-2,3,5-tri-O-benzoyluridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1]. 5-Azidomethyl-2-beta-methyl-2,3,5-tri-O-benzoyluridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C(NC(C(CN=[N+]=[N-])=C1)=O)N1[C@@H]2O[C@H](COC(C3=CC=CC=C3)=O)[C@@H](OC(C4=CC=CC=C4)=O)[C@@]2(C)OC(C5=CC=CC=C5)=O

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