5-Azidomethyl-2-beta-methyl uridine [2305415-72-7]
HY-152514
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product Name5-Azidomethyl-2-beta-methyl uridine [2305415-72-7]
- Delivery Days Customer10
- CAS Number2305415-72-7
- CertificationResearch Use Only
- Molecular FormulaC11H15N5O6
- Molecular Weight313.27
- Scientific Description5-Azidomethyl-2-beta-methyl uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. 5-Azidomethyl-2-beta-methyl uridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- SMILESO=C(C(CN=[N+]=[N-])=CN1[C@H]2[C@@](O)(C)[C@H](O)[C@@H](CO)O2)NC1=O
- UNSPSC41115811