5-(E)-VPG Phosphoramidite

MedChem Express

5-(E)-VPG Phosphoramidite

999

Research Use Only

C37H59N7O13P2

871.85

5-(E)-VPG Phosphoramidite (5(E)-VP-2-OMe-iBu-GPhosphoramidite) is a structurally modified phosphoramidite reagent used to synthesize biologically stable oligonucleotides. 5-(E)-VPG Phosphoramidite (POM) carries a VP protecting group and can be coupled to the target oligonucleotide at the 5 end via solid-phase synthesis. The modified oligonucleotide is then constructed through oxidation and deprotection steps. 5-(E)-VPG Phosphoramidite is suitable for RNAi and viral replication research[1].

CC(C)N(C(C)C)P(O[C@H]1[C@@H](OC)[C@H](N2C(N=C(NC(C(C)C)=O)NC3=O)=C3N=C2)O[C@@H]1/C=C/P(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)OCCC#N

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