5-Fluorouracil [51-21-8]

MedChem Express

5-Fluorouracil [51-21-8]

10

51-21-8

Research Use Only

99.99

C4H3FN2O2

130.08

5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[1][2]. 5-Fluorouracil also inhibits HIV[3].

O=C(N1)NC=C(F)C1=O

2°C to 8°C

12352200