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5-hydroxy Diclofenac [69002-84-2]

5-hydroxy Diclofenac [69002-84-2]

T37917
TargetMol Chemicals
CAS Number69002-84-2
Product group Chemicals
Molecular Weight312.15
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    5-hydroxy Diclofenac [69002-84-2]
  • Delivery Days Customer
    16
  • CAS Number
    69002-84-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    5-hydroxy Diclofenac
  • Molecular Formula
    C14H11Cl2NO3
  • Molecular Weight
    312.15
  • Scientific Description
    5-hydroxy Diclofenac is a metabolite of the NSAID diclofenac formed by the cytochrome P450 (CYP) isoform CYP3A4. Diclofenac is a non-selective COX inhibitor. It inhibits human COX-1 and -2 with IC50 values of 0.9-2.7 and 1.5-20 microM, respectively. Diclofenac inhibits ovine COX-1 and -2 with IC50 values of 60 and 220 nM, respectively.
  • Shelf life instruction
    3 years
  • SMILES
    OC(=O)Cc1cc(O)ccc1Nc1c(Cl)cccc1Cl
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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