5-Hydroxymethylcytosine / 5-hmC antibody [GT13612]
GTX629765
ApplicationsDot Blot, Electron Microscopy, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
Product group Antibodies
ReactivityOther Species
Overview
- SupplierGeneTex
- Product Name5-Hydroxymethylcytosine / 5-hmC antibody [GT13612]
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsDot Blot, Electron Microscopy, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDGT13612
- Concentration0.81 mg/ml
- ConjugateUnconjugated
- HostMouse
- IsotypeIgG2b
- ReactivityOther Species
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
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- Yan XX, Guo N, Ru SW, et al. The deficiency of 5-methylcytosine (5mC) and its ramification in the occurrence and prognosis of colon cancer. Medicine (Baltimore). 2023,102(34):e34860. doi: 10.1097/MD.0000000000034860Read this paper
- Huang R, Wang Y, Ge H, et al. Restoration of TET2 deficiency inhibits tumor growth in head neck squamous cell carcinoma. Ann Transl Med. 2020,8(6):329. doi: 10.21037/atm.2020.02.145Read this paper
- Wu J, Li H, Shi M, et al. TET1-mediated DNA hydroxymethylation activates inhibitors of the Wnt/β-catenin signaling pathway to suppress EMT in pancreatic tumor cells. J Exp Clin Cancer Res. 2019,38(1):348. doi: 10.1186/s13046-019-1334-5Read this paper
- Yatagai N, Saito T, Akazawa Y, et al. TP53 inactivation and expression of methylation-associated proteins in gastric adenocarcinoma with enteroblastic differentiation. Virchows Arch. 2019,474(3):315-324. doi: 10.1007/s00428-018-2508-9Read this paper
- Sun J, He X, Zhu Y, et al. SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function. Cell Stem Cell. 2018,23(3):355-369.e9. doi: 10.1016/j.stem.2018.07.018Read this paper
- Hsieh MC, Ho YC, Lai CY, et al. Melatonin impedes Tet1-dependent mGluR5 promoter demethylation to relieve pain. J Pineal Res. 2017,63(4). doi: 10.1111/jpi.12436Read this paper
- Hsieh MC, Lai CY, Ho YC, et al. Tet1-dependent epigenetic modification of BDNF expression in dorsal horn neurons mediates neuropathic pain in rats. Sci Rep. 2016,6:37411. doi: 10.1038/srep37411Read this paper